Veena Sangwan Selected Research

triptolide

7/2019	Correction: Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.
12/2015	Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma.
11/2015	Minnelide effectively eliminates CD133(+) side population in pancreatic cancer.
6/2015	Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.
5/2015	Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.
12/2014	Wild-type p53 reactivation by small-molecule Minnelide™ in human papillomavirus (HPV)-positive head and neck squamous cell carcinoma.
8/2014	Sorafenib and triptolide as combination therapy for hepatocellular carcinoma.
6/2014	Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway.
6/2014	Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.
11/2013	Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.

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Veena Sangwan Research Topics

Disease

22	Neoplasms (Cancer) 10/2021 - 02/2005
15	Pancreatic Neoplasms (Pancreatic Cancer) 07/2019 - 08/2010
5	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2013
3	Adenocarcinoma 10/2021 - 08/2010
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2019 - 01/2013
1	Stomach Neoplasms (Stomach Cancer) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2021
1	Triple Negative Breast Neoplasms 10/2021
1	Esophageal Neoplasms (Esophageal Cancer) 01/2020
1	Breast Neoplasms (Breast Cancer) 11/2019
1	Chronic Pancreatitis 12/2016
1	Renal Cell Carcinoma (Grawitz Tumor) 12/2015
1	Colonic Neoplasms (Colon Cancer) 06/2015
1	Colorectal Neoplasms (Colorectal Cancer) 06/2015
1	Squamous Cell Carcinoma of Head and Neck 12/2014
1	Hepatocellular Carcinoma (Hepatoma) 08/2014
1	Tics (Tic) 05/2014
1	Osteosarcoma (Osteogenic Sarcoma) 07/2013
1	Neuroblastoma 04/2013
1	Lung Neoplasms (Lung Cancer) 01/2013
1	Cholangiocarcinoma 06/2011
1	Liver Failure 01/2006
1	Weight Gain 01/2006
1	Insulin Resistance 01/2006

Drug/Important Bio-Agent (IBA)

17	triptolideIBA 07/2019 - 08/2010
12	14-O-phosphonooxymethyltriptolide disodium saltIBA 12/2015 - 10/2012
7	DiterpenesIBA 05/2015 - 10/2012
6	Proteins (Proteins, Gene)FDA Link 12/2016 - 01/2012
4	Pharmaceutical PreparationsIBA 01/2020 - 05/2014
4	ProdrugsIBA 11/2015 - 07/2013
3	CaspasesIBA 06/2015 - 08/2010
2	Sp1 Transcription FactorIBA 07/2019 - 11/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2015 - 06/2014
2	LigandsIBA 12/2015 - 06/2014
2	Death Domain ReceptorsIBA 12/2015 - 06/2014
2	Small Interfering RNA (siRNA)IBA 01/2012 - 06/2011
1	LipopolysaccharidesIBA 01/2022
1	AntigensIBA 01/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 10/2021
1	Superoxides (Superoxide)IBA 10/2021
1	Ethanol (Ethyl Alcohol)IBA 10/2021
1	matrigelIBA 10/2021
1	AlginatesIBA 10/2021
1	Biocompatible Materials (Biomaterials)IBA 10/2021
1	GelatinIBA 10/2021
1	HydrogelsIBA 10/2021
1	Conditioned Culture MediaIBA 01/2020
1	SuspensionsIBA 01/2020
1	Estrogen ReceptorsIBA 11/2019
1	Cyclin D1IBA 11/2019
1	CyclinsIBA 11/2019
1	palbociclibIBA 11/2019
1	Eukaryotic Initiation Factor-4A (Eukaryotic Initiation Factor 4A)IBA 11/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 12/2016
1	Pimozide (Orap)FDA Link 12/2016
1	Haloperidol (Haldol)FDA LinkGeneric 12/2016
1	AnnexinsIBA 06/2015
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 06/2015
1	Caspase 3 (Caspase-3)IBA 05/2015
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 05/2015
1	Transcription Factors (Transcription Factor)IBA 05/2015
1	Annexin A5IBA 05/2015
1	Oncogene Proteins (Oncogene Protein)IBA 12/2014
1	Antineoplastic Agents (Antineoplastics)IBA 08/2014
1	Sorafenib (BAY 43-9006)FDA Link 08/2014
1	Inositol (Myoinositol)IBA 06/2014
1	EnzymesIBA 06/2014
1	Phosphotransferases (Kinase)IBA 06/2014
1	Peptide Initiation Factors (Initiation Factor)IBA 06/2014
1	Apoptosis Regulatory ProteinsIBA 09/2013
1	Synthetic DrugsIBA 07/2013
1	Molecular Chaperones (Chaperone, Molecular)IBA 07/2013
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 07/2013
1	MicroRNAs (MicroRNA)IBA 07/2013
1	NF-kappa B (NF-kB)IBA 04/2013
1	RNA (Ribonucleic Acid)IBA 01/2012
1	Peptides (Polypeptides)IBA 01/2012
1	Cathepsin BIBA 01/2012
1	Glycoproteins (Glycoprotein)IBA 01/2012
1	GO 201IBA 01/2012
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 01/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2005

Therapy/Procedure

8	Therapeutics 01/2020 - 09/2013
2	Drug Therapy (Chemotherapy) 07/2013 - 08/2010
1	Transplantation 10/2021
1	Precision Medicine 01/2020